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CORE--ANIMAL

$321,210P01FY2000AGNIH

Mount Sinai School Of Medicine Of Cuny, New York NY

Investigators

Linked publications & trials

Abstract

The animal core will provide program project investigators with access to aged rhesus macaques and an extensive biomarker database. A colony of thirty aged female rhesus and additional young control females will be maintained in the California Regional Primate Research Center for behavioral and neuroanatomical studies. The biomarker data base will include daily determination of menses cycle activity, monitoring of reproductive hormone metabolites in the urine, serum hormone levels, and routine clinical parameters such as complete blood counts, serum chemistries, and urinalysis. For study designs which require ovariectomized animals, the animal core will perform bilateral ovarictomies on aged females or young controls, and estradiol replacement, and conditioning for animal handling and transport. Macaque reproductive and physiological parameters will be provided to Core Band made easily accessible to all investigators for experimental analysis.

View original record on NIH RePORTER →