CORE--TRANSGENIC ANIMAL MODEL DEVELOPMENT

$156,563P30FY2005AGNIH

University Of Washington, Seattle WA

Investigators

Linked publications & trials

Paper 39388265 Paper 39386547 Paper 39345368 Paper 39145448 Paper 39091744 Paper 39055969 Paper 39005259 Paper 38895256 Paper 38802544 Paper 38645098 Paper 38617345 Paper 38559208 Paper 38405950 Paper 38328214 Paper 38167865 Paper 37952157 Paper 37932399 Paper 37742081 Paper 37683181 Paper 37462785 Paper 37461091 Paper 37398334 Paper 37365290 Paper 37289866 Paper 36877298 Paper 36873708 Paper 36840897 Paper 36799301 Paper 36562924 Paper 36204043 Paper 36179270 Paper 36165806 Paper 36044277 Paper 35948858 Paper 35861821 Paper 35858543 Paper 35798912 Paper 35695982 Paper 35448464 Paper 35428698 Paper 35416576 Paper 35320492 Paper 35089871 Paper 35019203 Paper 34793210 Paper 34751131 Paper 34704522 Paper 34662414 Paper 34545808 Paper 34536202 Paper 34382643 Paper 34297314 Paper 34232461 Paper 34129171 Paper 34080150 Paper 33864592 Paper 33791939 Paper 33790287 Paper 33744869 Paper 33665645 Paper 33595768 Paper 33504426 Paper 33463526 Paper 33446907 Paper 33377274 Paper 33324011 Paper 33319746 Paper 33101276 Paper 32990683 Paper 32990592 Paper 32821821 Paper 32779818 Paper 32648907 Paper 32648542 Paper 32644988 Paper 32578074 Paper 32554501 Paper 32432546 Paper 32399915 Paper 32368707 Paper 32366330 Paper 32342860 Paper 32331968 Paper 32310227 Paper 32234964 Paper 32190787 Paper 32190786 Paper 32145284 Paper 31984744 Paper 31975050 Paper 31844058 Paper 31823466 Paper 31728898 Paper 31714209 Paper 31650481 Paper 31511839 Paper 31385433 Paper 31353411 Paper 31235724 Paper 30718408

Abstract

SPECIFIC AIMS 1. Continue to develop new genetically altered animal models for studying mechanisms of the biology of aging. 2. Provide a resource that enables University of Washington Health Sciences faculty involved in various aging projects to utilize genetic engineering technology for answering basic questions about the biology of aging. 3. Provide a resource and expertise in the construction of targeting vectors, injectable DNA constructs and inducible promoters systems for generating genetically altered animal models of the biology of aging. 4. Accelerate and enhance cryopreservation of embryos and sperm from useful genetically altered mouse models of aging for repository storage and conservation of housing resources. 5. Provide a training resource for fellows and junior faculty in transgenic and embryonic stem cell technology.

View original record on NIH RePORTER →