Scientific Core

$60,290P01FY2005CANIH

Yale University, New Haven CT

Investigators

Linked publications & trials

Paper 38635661 Paper 34903581 Paper 33785601 Paper 33414189 Paper 32521275 Paper 32272661 Paper 31524859 Paper 31461506 Paper 31353209 Paper 31068430 Paper 31039329 Paper 30955494 Paper 30383841 Paper 30122350 Paper 30068640 Paper 30021895 Paper 30006461 Paper 29643239 Paper 29527542 Paper 29058661 Paper 28584122 Paper 28117770 Paper 27872311 Paper 27855219 Paper 27659050 Paper 27335146 Paper 27134163 Paper 27006465 Paper 26952103 Paper 26951683 Paper 26933051 Paper 26766042 Paper 26646615 Paper 26292323 Paper 26291450 Paper 26220997 Paper 26200477 Paper 26121143 Paper 26116541 Paper 25950714 Paper 25855729 Paper 25792595 Paper 25702134 Paper 25693203 Paper 25662012 Paper 25227470 Paper 25166506 Paper 25087050 Paper 25047834 Paper 24823351 Paper 24821854 Paper 24807711 Paper 24732912 Paper 24725595 Paper 24705134 Paper 24679528 Paper 24667711 Paper 24659628 Paper 24525741 Paper 24441309 Paper 24360278 Paper 24222489 Paper 23937650 Paper 23871219 Paper 23625009 Paper 23569269 Paper 23438856 Paper 23097423 Paper 23077295 Paper 23012480 Paper 22840393 Paper 22836356 Paper 22745225 Paper 22514351 Paper 22473208 Paper 22056390 Paper 22022268 Paper 21925386 Paper 21828240 Paper 21673190 Paper 21536868 Paper 21411522 Paper 21376359 Paper 21233201 Paper 21187425 Paper 21139068 Paper 21109672 Paper 20861250 Paper 20808903 Paper 20719877 Paper 20558719 Paper 20219930 Paper 20006367 Paper 19889776 Paper 19754429 Paper 19729838 Paper 19690161 Paper 19656890 Paper 19631767 Paper 19306280

Abstract

The long-term objective of the Scientific Core is to provide state-of-the-art Core facilities that support each of the four projects of the Program. Core B is composed of a Phosphorimager facility and a protein expression and purification facility, as well as other shared facilities including a dark room and liquid nitrogen freezers. The Phosphorimager will be used for imaging and quantification of various results including primer-extension assays, gel mobility shifts, and Western blots. The protein expression and purification facility consists of a shaking incubator, a centrifuge, an FPLC, and protein expression vectors. It is used to express and purify proteins that are studied in each of the projects. The Scientific Core also possesses liquid nitrogen freezers for the storage of cell lines and a gel documentation system. In addition, expertise is provided to all member laboratories by personnel who oversee the Core. This Scientific Core is essential to the success of the Program, and serves to facilitate interaction between member laboratories.

View original record on NIH RePORTER →