24,25(OH)2D3 FOR SUPPRESSION OF HYPERPARATHYROIDISM IN X LINKED RICKETS

$0M01FY2000RRNIH

Yale University, New Haven CT

Investigators

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Abstract

Effectiveness and safety of 24,25(OH)2D3 for suppression of hyperparathyroidism often present in patients with X-linked hypophosphatemic rickets (XLH) will be assessed. Optimal dose of 24,25(OH)2D3 for PTH suppression will be established. Both acute and chronic suppression will be examined in a double-blind, placebo-controlled fashion.

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