ROLE OF BACTERIAL SUPERANTIGENS IN TOURETTE'S SYNDROME

$25,789M01FY2000RRNIH

Yale University, New Haven CT

Investigators

Linked publications & trials

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Abstract

There is mounting evidence that microbial pathogens (particularly group A beta-hemolytic streptococci, GABHS) trigger acute episodes of Tourette's Syndrome (TS). Determining whether changes in the peripheral blood T lymphocyte population coincide with acute exacerbations of Tourette's Syndrome (TS) symptoms will be studied as well as identification of bacterial pathogens in the oropharynx or stool that initiate acute TS episodes. This is an ongoing study.

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