EFFECTS OF PUBERTY ON GLUCOSE KINETICS

$25,789M01FY2000RRNIH

Yale University, New Haven CT

Investigators

Linked publications & trials

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Abstract

The psysiologic and hormonal changes of puberty impair insulin action. This protocol examines the kinetic mechanisms underlying this alteration in insulin responsiveness. Most recently the microdialysis technique has been used to study the biochemical milieu of the adipose and muscle tissues in healthy children and those with obesity and diabetes. The newer studies have produced new insights into adipose and muscle metabolism.

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