COMPARISON OF GM/CSF TREATMENT OF SEPTIC NEONATES
$0M01FY2000RRNIH
Weill Medical College Of Cornell Univ, New York NY
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Abstract
Neonatal immune system is deficient in qualitative and quantitative functions of neutrophils. We propose to compare two cytokines (GM-CSF and G-CSF) in their ability to improve these functions during sepsis in a prospective, randomized clinical trial septic neonates will be treated with either cytokine. Time required to reconstitute normal neutrophil number and function will be compared. Signs of toxicity will be followed, as well.
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