GOG 172:IV PACLITAXEL &CISPLATIN VS IV PACLITAXEL IN EPITHELIAL OVAR

$0M01FY2000RRNIH

Tulane University Of Louisiana, New Orleans LA

Investigators

Linked publications & trials

Paper 27803104 Paper 26770763 Paper 25648541 Paper 25401485 Paper 25109932 Paper 24925880 Paper 24613295 Paper 24516231 Paper 24415732 Paper 24271347 Paper 24219913 Paper 24046302 Paper 23727086 Paper 23677024 Paper 23619080 Paper 23419804 Paper 23349510 Paper 23269790 Paper 23076013 Paper 23068916 Paper 22981277 Paper 22867730 Paper 22853972 Paper 22658574 Paper 22554719 Paper 22497791 Paper 22483359 Paper 22480598 Paper 22465315 Paper 22446176 Paper 22019225 Paper 22019221 Paper 21985788 Paper 21921144 Paper 21904395 Paper 21896829 Paper 21783289 Paper 21742304 Paper 21705121 Paper 21673295 Paper 21554737 Paper 21525746 Paper 21396623 Paper 21389978 Paper 21382989 Paper 21350366 Paper 21239359 Paper 20930087 Paper 20929989 Paper 20861271 Paper 20847142 Paper 20825306 Paper 20822371 Paper 20660819 Paper 20618702 Paper 20533872 Paper 20531015 Paper 20511979 Paper 20399927 Paper 20389058 Paper 20173677 Paper 20123264 Paper 20019670 Paper 19541818 Paper 19395280 Paper 19366774 Paper 19200445 Paper 19194319 Paper 19000014 Paper 18663165 Paper 18593763 Paper 18577469 Paper 18413195 Paper 18401832 Paper 18227407 Paper 18226670 Paper 18215978 Paper 18205225 Paper 18191094 Paper 18173357 Paper 18025875 Paper 18024536 Paper 17978591 Paper 17935800 Paper 17682123 Paper 17651776 Paper 17623996 Paper 17610099 Paper 17599428 Paper 17582655 Paper 17509588 Paper 17456892 Paper 17451422 Paper 17407044 Paper 17389292 Paper 17387446 Paper 17258320 Paper 17255739 Paper 17230416 Paper 17213921

Abstract

The standard treatment for optimally debulked Stage III ovarian or primary peritoneal carcinoma is chemotherapy with intravenous Cisplatin and Paclitaxel. The purpose of this study is to determine the effectiveness of administration of chemotherapy into the abdominal cavity in addition to intravenous chemotherapy compared to the current standard intravenous chemotherapy. Because ovarian cancer spreads in the abdominal cavity, giving chemotherapy by infusion into the abdominal cavity may result in a greater dose of the drugs reaching tumor cells. This study will evaluate the patient's response, and survival/disease free interval when treated with standard intravenous Cisplatin and Paclitaxel compared to intravenous Paclitaxel and intraperitoneal Cisplatin and Paclitaxel. The study will also evaluate the impact of treatment on the patient's quality of life.

View original record on NIH RePORTER →