COMBINATION PACLITAXEL/L778,123 IN SOLID TUMORS

$0M01FY2000RRNIH

University Of Texas Hlth Sci Ctr San Ant, San Antonio TX

Investigators

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Abstract

The combination of L-778123, a potent inhibitor of human farnesyl-protein transferase, and paclitaxel, a widely used chemotherapeutic agent used to treat a number of tumors, will be studied. The main objective is to determine the maximum tolerated dose of the drug combination and evaluate efficacy.

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