ZOLEDRONATE VS AREDIA IN MULTIPLE MYELOMA/BREAST CANCER W /BONE DISORDERS

$0M01FY2000RRNIH

University Of Texas Hlth Sci Ctr San Ant, San Antonio TX

Investigators

Linked publications & trials

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Abstract

This is a phase III trial of Zoledronate, a third generation bisphosphonate which is a more potent inhibitor of osteoclasts than earlier bisphosphonates, in two dose levels verskus pamidronate (Aredia). The latter drug has been shown (in combination with anti-neoplastic agents) to decrease significantly the proportion of patients with skeletal complications due to lytic bone disease associated with multiple myeloma and breast cancer.

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