PHASE I TRIAL OF BIZELESIN USING SINGLE BOLUS INFUSION EVERY 28 DAYS

$16,409M01FY2000RRNIH

University Of Texas Hlth Sci Ctr San Ant, San Antonio TX

Investigators

Linked publications & trials

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Abstract

The purposes of this study are to determine the maximum tolerated dose of bizelesin given as a ten minute infusion and repeated every 28 days; to determine the qualitative and quantitative toxicities of bizelesin given as a ten minute infusion; to characterize the pharmacokinetics; to determine the recommended dose; and to collect information about the antitumor effects of bizelesin in patients with advanced cancer.

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