PALIVIZUMAB PROPHYLAXIS IN CONGENITAL HEART DISEASE CHILDREN

$0M01FY2000RRNIH

University Of California San Francisco, San Francisco CA

Investigators

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Abstract

The purpose of this study are to: 1) describe the safety and tolerance of palivizumab, compared with placebo, in children with congenital heart disease and; 2) to determine palivizumab serum concentrations for all children at baseline ant at the trough after the fourth injection. Patients who are placed on cardiopulmonary bypass for surgery will have pre- and post-bypass concentrations determined to study the effect of bypass on palivizumab concentrations.

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