CIRCADIAN RHYTHM OF INTRAOCULAR PRESSURE IN HUMAN SUBJECTS

$22,433M01FY2000RRNIH

University Of New Mexico, Albuquerque NM

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Abstract

The object of this study is 1) whether statistically and biologically significant differences in IOP occur in subjective dark versus subjective light phases in light-entrained human subjects; and if so, 2) location of the peak and nadir values in relation to the dark and light phases; 3) the goodness of fit of the data to circadian cosinor function tests; 4) whether established CRIOP amplitude parameters for diagnosis of pressure pathology are statistically consistent with the observed results of the proposed study.

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