TOLERATION &BIOAVAILABILITY OF INHALED INSULIN IN ASTHM

$0M01FY2000RRNIH

University Of Virginia Charlottesville, Charlottesville VA

Investigators

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Abstract

Currently, insulin can only be given by injection. Pfizer, Inc., and Inhale Therapeutic Systems, have developed a dry powder insulin formulation and aerosol delivery device that safely delivers a rapid acting insulin by forming an insulin cloud that patients can inhale into their lungs where it is then absorbed. Since chronic inflamation or a decrease in pulmonary function can reduce the tolerance and bioavailability of inhaled medications, this study will measure changes in the moderate to severe asthmatic.

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