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INFLUENCE OF POSTMENOPAUSAL ESTROGEN REPLACEMENT ON GH AUTO NEG FEEDBACK

$28,104M01FY2000RRNIH

University Of Virginia Charlottesville, Charlottesville VA

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Abstract

Estrogen's influence on GH secretion is significantly responsible for the age and gender differences in GH secretory profiles. We will test the hypothesis that estrogen replacement in postmenopausal women increases growth hormone (GH) secretion by decreasing the ability of GH to negatively regulate its own secretion basally and GH secretion stimulated by growth hormone releasing hormone (GHRH), growth hormone releasing peptide-2 (GHRP-2), and exercise.

View original record on NIH RePORTER →