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SIGNALING IN ALLERGIC INFLAMMATION--KININS AND ASTHMA

$0M01FY2000RRNIH

Scripps Research Institute, La Jolla CA

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Linked publications & trials

Abstract

Kinins are important participants in the cascade of events leading to IgE-mediated chronic airway inflammation, and consequent clinical disease. This project aims to investigate the mechanism(s) by which kinins contribute to the development of allergic airway disease. We hypothesize that kinin-stimulated inflammatory gene expression provides critical signals, bridging the progression of acute allergic reactions into chronic airway inflammation.

View original record on NIH RePORTER →