HP-228 AND PLACEBO WITH PCA MORPHINE FOLLOWING TOTAL HIP REPLACEMENT

$27,361M01FY2000RRNIH

Scripps Research Institute, La Jolla CA

Investigators

Linked publications & trials

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Abstract

Patients undergoing total hip replacement are being enrolled into this dose-escalating study evaluating a cytokine compound in comparison to morphine and placebo. One patient has been withdrawn because of an eoisode of hypotension after receiving first dose of drug. Sixty-four other patients have completed the study with no serious adverse effects. Recruitment is ongoing.

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