ETODOLAC SENSITIZATION OF CLL CELL TO CHEMOTHERAPEUTICS

$0M01FY2000RRNIH

University Of California San Diego, La Jolla CA

Investigators

Linked publications & trials

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Abstract

Determine if the chronic lymphocytic leukemia cells of patients given etodolac for one day demonstrate increased sensitivity in vitro to fludarabine, chlorodeoxyadenosine, dexamethasone, and chlorambucil, determine which enantiomer of etodolac confers such chemotherapeutic sensitivity, and determine the mechanism of action of etodolac toward the malignant lymphocytes.

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