PHASE I STUDY OF CD40 LIGAND TRANSDUCED LEUKEMIA CELLS IN CLL

$0M01FY2000RRNIH

University Of California San Diego, La Jolla CA

Investigators

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Abstract

Determine the tolerability of recombinant CD40-L-transduced autologous human leukemia cells given as intravenous injection, determine local, regional and systemic toxicity, determine the maximum tolerated dose, determine safety of low dose interleukin-2 along with modified leukemia cells for maximum dose.

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