ORAL NICTOTINIC ACID FOR TREATMENT OF LESCH NYHAN PATIENTS

$0M01FY2000RRNIH

University Of California San Diego, La Jolla CA

Investigators

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Abstract

Evaluate the possible therapeutic benefit of oral doses of nicotinic acid for reducing the high intracellular content of phosphoribosyl pyrophosphate found in patients with Lesch-Nyhan disease and thereby ameliorate the clinical features of the disease.

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