ANTI TNF CHIMERIC MONOCLONAL ANTIBODY IN ACUTE RHEUMATOID ARTHRITIS

$0M01FY2000RRNIH

University Of California San Diego, La Jolla CA

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Abstract

EVALUATE SAFETY AND EFFICACY AND CHRONIC TREATMENT WITH cA2 IN COMBINATION WITH MTX IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS DESPITE TREATMENT WITH METHOTREXATE (MTX). ALSO EVALUATE REDUCTION IN SIGNS AND SYMPTOMS OF DISEASE, REDUCTION OF DISABILITY, RETARDATION OF JOINT DAMAGE, DISEASE REMISSION AND QUALITY OF LIFE IMPROVEMENT AT ONE YEAR FOLLOWING ONSET OF TREATMENT.

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