EFFECTS OF K MG CITRATE ON INSULIN SENSITIVITY IN GOUTY DIATHESIS

$0M01FY2000RRNIH

University Of Texas Sw Med Ctr/Dallas, Dallas TX

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Abstract

The overall aim of this project is to evaluate the efficacy of oral administration of K-Mg-Citrate in improving insulin sensitivity in subjects with gouty diathesis. Gouty diathesis is a metabolic disturbance characterized by excessive urinary acidity that predisposes one to the development of uric acid and calcium renal stones. The hypothesis tested in this study is that therapy with K-Mg-Citrate increases both insulin-mediated glucose disposal and urinary pH in patients with gouty diathesis.

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