CAUSES AND MANAGEMENT OF PRIMARY HYPERCHOLESTEROLEMIA

$0M01FY2000RRNIH

University Of Texas Sw Med Ctr/Dallas, Dallas TX

Investigators

Linked publications & trials

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Abstract

This project examines lipoprotein defects, evaluates clinical significance and the need to treat. Treatment options under investigation include role of individual dietary fatty acids and the mode of action, safety and efficacy of single and combined drug therapy. Metabolic diet studies are conducted, as well as, kinetic studies. Metabolism and underlying defects in lipoproteins are being minutely analysed. Source of research material is plasma lipoproteins through- out the different study phases. LDL/VLDL turnover studies will be utilized.

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