INSULIN DEPRIVATION ON REGIONAL SUBSTRATE METABOLISM IN KIDNEY

$0M01FY2000RRNIH

Mayo Clinic Coll Of Medicine, Rochester, Rochester MN

Investigators

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Abstract

The specific aims of the study are to determine if IDDM subjects will display high rates of renal amino acid uptake and oxidation during insulin depletion and if the reamination of KIC to leucine serves to transfer nitrogen from the kidney to extrarenal tissue during insulin depletion.

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