IN VIVO REGULATION OF PROTEIN TURNOVER BY HORMONES

$0M01FY2000RRNIH

Mayo Clinic Coll Of Medicine, Rochester, Rochester MN

Investigators

Linked publications & trials

Paper 37717845 Paper 35005320 Paper 34554658 Paper 34401721 Paper 33305291 Paper 33193667 Paper 32807060 Paper 32634120 Paper 32184195 Paper 31944322 Paper 31874800 Paper 31570296 Paper 31171572 Paper 31088850 Paper 30922668 Paper 30753254 Paper 30591038 Paper 29907861 Paper 29854969 Paper 29564978 Paper 29498141 Paper 29306517 Paper 29290310 Paper 29203126 Paper 29118087 Paper 28787318 Paper 28532709 Paper 28529823 Paper 28483801 Paper 28460625 Paper 28248413 Paper 28183453 Paper 28027795 Paper 27993381 Paper 27779124 Paper 27549073 Paper 27484667 Paper 27410922 Paper 27310030 Paper 26885881 Paper 26823553 Paper 26806605 Paper 26797708 Paper 26741885 Paper 26547226 Paper 26231556 Paper 25840581 Paper 25755013 Paper 25612167 Paper 25516026 Paper 25486131 Paper 25399733 Paper 25399731 Paper 25075259 Paper 24952654 Paper 24904092 Paper 24707319 Paper 24659368 Paper 24639405 Paper 24586359 Paper 24576800 Paper 24458996 Paper 24183837 Paper 24155251 Paper 24139354 Paper 24107679 Paper 24095618 Paper 23820622 Paper 23639599 Paper 23639598 Paper 23591988 Paper 23520042 Paper 23481224 Paper 23467205 Paper 23443923 Paper 23436338 Paper 23418085 Paper 23418014 Paper 23417995 Paper 23307874 Paper 23261228 Paper 23122799 Paper 23109068 Paper 23089511 Paper 23008132 Paper 23007134 Paper 22933539 Paper 22772314 Paper 22766768 Paper 22570948 Paper 22467464 Paper 22415196 Paper 22344503 Paper 22338076 Paper 22300408 Paper 22288893 Paper 22221344 Paper 22212966 Paper 22205355 Paper 22194324

Abstract

The purpose of this study is to better understand how insulin affects protein metabolism in humans. The specific aims are to determine the effect of intraarterial infusion of insulin on fractional synthesis rate of myosin and mixed muscle proteins in normal subjects and Type I diabetic patients, determine dose-related effect of insulin on protein dynamics, and to determine the validity of using Apo B as a marker of AA-tRNA label in liver in the fasted state during insulin infusion with or without amino acid replacement.

View original record on NIH RePORTER →