Arginine stimulation as a measure of insulin reserve &the familial incidence of

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La Biomed Res Inst/ Harbor Ucla Med Ctr, Torrance CA

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Abstract

To classify children and adolescents with diabetes as having type 1 or type 2 diabetes, and to determine how common undiagnosed diabetes is in their siblings and parents. The currently available test to diagnose type 1 vs type 2 diabetes are not always reliable. We propose to use an intravenous arginine stimulation test to measure insulin reserve and thus, differentiate between type 1 and type 2 diabetes in children and adolescents. To determine how common undiagnosed diabetes is in relatives of children and adolescents with type 1 and type 2 diabete.

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