MECHANISM OF ETHNIC DIFFERENCES IN PSYCHOTROPHIC RESPONSES

$982M01FY2000RRNIH

La Biomed Res Inst/ Harbor Ucla Med Ctr, Torrance CA

Investigators

Linked publications & trials

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Abstract

To compare the response and explore potential reasons for differences in response to psychotropic medication in different ethnic groups. The factors hypothesized in determining response are: inherited differences in drug metabolizing liver enzyme systems, protein binding, and dietary influences. To evaluate subjects from African-American, Asian, Caucasian and Hispanic backgrounds with extensive physical and laboratory examinatins. The investigatin will be composed of two parts: pharmacogenetics & protein binding and dietary influences.

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