STRUCTURAL-FUNCTIONAL RELATIONSHIPS IN DIABETIC NEPHROPATHY

$0M01FY2000RRNIH

University Of Minnesota Twin Cities, Minneapolis MN

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Abstract

This protocol has two major purposes. First, we are examining structural-functional relationships in diabetic nephropathy using quantitative light and electron microscopic morphometry to determine the structural substrates for microalbuminuria, proteinuria, hypertension and declining GFR. Secondly, we are examining the effects of pancreas transplant on the established lesions of diabetic nephropathy.

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