SPECT IMAGING OF DOPAMINE RECEPTORS WITH EPIDEPRIDE &ALPHA METHYL PARA TYROSINE

$34,535M01FY2000RRNIH

Yale University, New Haven CT

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Abstract

We developed, in healthy subjects, a method to measure synaptic dopamine levels by measuring the number of dopamine D2 receptors unmasked when dopamine is depleted with a synthesis inhibitor (alpha-methyl-para-tyrosine).

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