ECOGC9741: ATC VS ACT AT 14 OR 21 DAYS NODE + STAGE II &IIIA BREAST NEOPLASM

$21,006M01FY2000RRNIH

New York University School Of Medicine, New York NY

Investigators

Linked publications & trials

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Abstract

This randomized Phase III trial will compare sequential chemotherapy with doxorubicin, paclitaxel, and cyclophosphamide to combined doxorubicin and cyclophosphamide followed by paclitaxel for disease-free and overall survival. The effect of increasing the dose intensity of adjuvant chemotherapy (decreasing the interval between chemotherapy courses from 21 to 14 days) on the disease-free interval and overall survival will be determined. The toxicities of these regimens will be determined.

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