Transgenic and Neurobehavior Core

$213,165P50FY2004NSNIH

Johns Hopkins University, Baltimore MD

Investigators

Linked publications & trials

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Abstract

The Transgenic and Neurobehavior Core B Facility has three major aims: 1. To generate and maintain breeding colonies oftransgenic and gene-targeted mouse lines and to provide cohorts of transgenic and gene-targeted mice for studies proposed in Projects #1 to #4 of the Center grant. 2. To establish C57B16 congenic lines of the transgenic mice used throughout the study. 3. To establish methods to examine motor and clinical deficits in mouse models of Parkinson's Disease. The transgenic and neurobehavior core will be a shared resource of the Parkinson's Disease Research Center and will play a central role in our investigations in the pathogenesis of Parkinson's Disease.

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