CYTOKINES AND SURFACE MOLECULES IN TUBERCULOSIS PATHOGENESIS

$21,006M01FY2000RRNIH

New York University School Of Medicine, New York NY

Investigators

Linked publications & trials

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Abstract

This study will test the hypothesis that the human host response in minorities to Mycobacterium tuberculosis is mediated by cytokines and surface molecules on mononuclear phagocytes that regulate the formation of granuloma and granulomatous inflammation. Subjects will be studied using brochoalveolar lavage and clinical biopsy material. The lab was used for the following: Laminar flow hoods, BAL analysis, DNA isolation, RNA isolation, ELISA, Recombinant DNA Technology, Northern Analysis, Western Analysis and ultracentrifugation.

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