FEXOFENADINE DISPOSITION IN HUMANS

$0M01FY2000RRNIH

Vanderbilt University, Nashville TN

Investigators

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Abstract

That fexofenadine disposition an is mediated by the drug efflux transporter, P-glycoprotein and may, therefore serve as an in vivo probe for such activity. SPECIFIC AIMS: To determine fexofenadine disposition as a probe of P-glycoprotein activity in vivo, in healthy African-American and Caucasian subjects.

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