CHLORZOXAZONE 6-HYDROXYLATION IN VIVO PROBE OF CP450

$0M01FY2000RRNIH

Vanderbilt University, Nashville TN

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Abstract

Investigate cytochrome P4502E1 activity in humans using chlorzoxazone 6- hydroxylation as an in vivo probe and to identify physiological determinants and other modulating factors such as age, disease states, and drug interactions.

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