Glycine and glutathione metabolism in healthy subjects

Massachusetts Institute Of Technology, Cambridge MA

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Linked publications & trials

Abstract

This protocol is a pilot study aimed to determine basic aspects of glycine and glutathione metabolism under conditions of a sulfur free amino acid diet. Cysteine availability is the rate limiting step in glutathione synthesis. We hypothesized that during a short term sulfur-free amino acid diet the rates of Glutathione synthesis are maintained at the expense of increased protein turnover.