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CALORIC RESTRICTION/PHYSICAL EXERCISE ON ENERGY METABOLISM--SEX DIFFERENCES

$40,417M01FY2000RRNIH

Massachusetts Institute Of Technology, Cambridge MA

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Abstract

To compare and contrast 1) changes in body composition, kinetics of major energy-yielding substrate metabolism in men and women, under resting conditions and during and following moderate exercise, during a three-week period of hypocaloric feeding. 2) kinetic and metabolic studies will include feasible and novel 24-hour stable isotope tracer-indirect calorimetry protocols, 3) explore the parameters outlined above under conditions of a balanced reduction in energy intake in comparison with a high protein/energy (lipid) dense hypocaloric diet in women and men.

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