PET investigation of serotonin activity in anorexia &bulimia nervosa

$0M01FY2000RRNIH

Children'S Hosp Pittsburgh/Upmc Hlth Sys, Pittsburgh PA

Investigators

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Abstract

To better define central nervous system serotonin (5-HT) activity in AN and BN when ill and after recovery. Position Emisson Tomography (PET) imaging with a serotonergic ligand, 7-18 altanserin is used to provide insight into the pathophysiology of the (5-HT) neuronal system in 5 groups of subjects, ill anorexia nervosa and bulimia nervosa, recovered anorexia nervosa and bulimia nervosa and normal controls.

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