PATHOLOGIC ALTERATIONS OF THYROID FUNCTION

$0M01FY2000RRNIH

Children'S Hosp Pittsburgh/Upmc Hlth Sys, Pittsburgh PA

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Abstract

Determine etiology and pathogenesis of abnormal thyroid hormone metabolism or secretion in Grave's Disease, Hashimoto's Disease, and congenital hypothyroidism. Hormonal homeostasis is assessed during hypo and hyperthyroidism to determine the role of altered thyroid hormone secretion in metabolic homeostasis.

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