LOW SALT, HIGH SALT, &HIGH SALT W/ KHCO3 IN POSTMENOPAUSAL WOMEN

$0M01FY2000RRNIH

University Of California San Francisco, San Francisco CA

Investigators

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Abstract

In this study postmenopausal women will have baseline markers of bone metabolism including serum calcium, phosphate, alk phos, sodium, potassium, creatinine, chloride, osteocalcin, PTH, and calcitriol, and 24-hour urine sodium, calcium, deoxypyridinoline, creatinine, potassium, and cyclic AMP. The women will then be adapted to a low-salt diet for four weeks, and these outcomes repeated. Then they will be randomized to a high-salt diet with placebo or a high-salt diet with potassium bicarbonate for four weeks and the outcomes repeated.

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