TUBERCULOSIS AND AIDS

$0M01FY2000RRNIH

University Of California San Francisco, San Francisco CA

Investigators

Linked publications & trials

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Abstract

We will determine and compare the multiple dose intrapulmonary pharmacokinetics and plasma concentrations of isoniazid, rifampin, and pyrazinamide in HIV-infected and uninfected patients who are being treated for pulmonary tuberculosis. The GCRC is critical to this study. Patients will undergo bronchoscopy and bronchoalveolar lavage, blood draws, and serial observations.

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