MECHANISMS OF FOOD HYPERSENSITIVITY IN ATOPIC DERMATITIS

$47,556M01FY2000RRNIH

Mount Sinai School Of Medicine Of Cuny, New York NY

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Abstract

Studies of dietary prophylaxis in newborns at high risk for atopic disease, and provocation of skin symptoms and immunologic changes by blinded food challenges strongly suggest a significant pathogenic role for IgE-mediated FH in AD. The purpose of this research is to more precisely define the natural history and immunopathogenic mechanisms of food hypersensitivity (FH) in children with atopic dermatitis (AD).

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