PSYCHOBIOLOGICAL ALTERATIONS IN AGING COMBAT VETERANS W/ PTSD

$47,556M01FY2000RRNIH

Mount Sinai School Of Medicine Of Cuny, New York NY

Investigators

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Abstract

This protocol will attempt to (1) evaluate feedback inhibition of the HPA axis in elderly combat veterans and controls; (2) assess suprapituitary activation of the HPA axis using the metyrapone stimulation test; (3) characterize lymphocyte glucocorticoid receptor activity as a measure of the dynamics of the HPA axis; and (4) charctarize the circadian rhythm of cortisol, ACTH, NE, and MHPG using chronobiological techniques.

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