ACTG 301 TRIAL OF MEMANTINE FOR AIDS DEMENTIA COMPLEX (ADC)

$47,556M01FY2000RRNIH

Mount Sinai School Of Medicine Of Cuny, New York NY

Investigators

Linked publications & trials

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Abstract

This is a randomized, double-blind, placebo-controlled trial of oral memantine taken alone or concurrently with an antiretroviral regimen in subjects with ADC stage 1, 2, or 3. This study will assess the possible efficacy of oral memantine in ameliorating AIDS Dementia, assess the possible efficacy of oral memantine in ameliorating painful peripheral neuropathy in HIV-infected subjects with ADC, and correlate dosing levels of memantine with observed toxicities and clinical outcomes.

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