SPECIFIC IMMUNITY DEVELOPMENT IN HUMAN NEWBORNS

$0M01FY2000RRNIH

University Of Colorado Denver, Aurora CO

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Abstract

This study looks at the outcome of Hepatitis B vaccination in prematures and term controls, testing the hypothesis that the T cell activation response to staph endotoxin B will predict the titer of antibody after 9 months. Cord blood is obtained at birth from prematures and a further four samples have been accrued in the past year. Permission to test the response, and to measure the antibody response to Hepatitis B is obtained at follow up. The total number of subjects being followed is currently 36, and the study will be closed to new entrants at this point.

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