CORDOX (F6P) ADJUNCT THERAPY IN ACUTE SICKLE CELL VASOOC

$0M01FY2000RRNIH

University Of Iowa, Iowa City IA

Investigators

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Abstract

The purpose of this study is to determine the efficacy of intravenous Cordox (fructose-1, 6-diphosphate) as adjunct therapy to parenteral narcotic analgesia (PNA), determine the lowest dose of intravenous Cordox that is significantly superior to placebo-PNA, and confirm the tolerability of multiple dose exposure to intravenous Cordox in sickle cell patients with painful vaso-occlusive episode.

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