MECHANISMS FOR CYTOKINE PRODUCTION IN SEPSIS INDUCED ACUTE LUNG INJURY

$22,028M01FY2000RRNIH

University Of Iowa, Iowa City IA

Investigators

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Abstract

This study is determining if multiple mitogen-activated protein kinase pathways are activated by endotoxin for optimal expression of cytokine genes and if endotoxin activates transcription factors that regulate expression of cytokine genes in human alveolar macrophages from healthy adults.

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