IV NICOTINE, NICOTINE PATCH &NICOTINE PLUS MECAMYLAMINE ON MRI

$0M01FY2000RRNIH

Medical College Of Wisconsin, Milwaukee WI

Investigators

Linked publications & trials

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Abstract

The purpose of this investigation is to: 1) determine the acute effects of nicotine patch on MRI parameters; 2) establish whether the acute MRI responses to IV nicotine are influenced by the nicotine patch; 3) establish the minimum interval between subsequent IV injections of nicotine that does not cause attentuation of the MRI response; and 4) compare the MRI signal changes following nicotine patch plus mecamylamine to those of nicotine patch alone.

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