GENETICS OF INHIBITOR DEVELOPMENT IN HEMOPHILIA

$0M01FY2000RRNIH

Medical College Of Wisconsin, Milwaukee WI

Investigators

Linked publications & trials

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Abstract

The investigator hypothesizes that a limited number of genetic factors determine the risk of inhibitor (anti-factor VIII antibodies) development in severe hemophilia A patients. Two hundred brother pairs will be recruited for DNA analysis of candidate genes and genome-wide scanning in order to identify genes responsible for the inhibitor factor.

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