SEROTONERGIC PHARMACOTHERAPY FOR AGITATION OF DEMENTIA

$0M01FY2000RRNIH

University Of Pittsburgh At Pittsburgh, Pittsburgh PA

Investigators

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Abstract

The primary goal of this acute, inpatient treatment protocol is to compare the putative, short-term benefit of the most selective and highly potent serotonin reuptake inhibitor (citalopram) and our usual pharmacotherapy (perphenazine) with placebo in reducing behavioral disturbances and/or psychosis associated with dementia. In addition, precise drug metabolic probes are used to identify those at risk of adverse psychotropic side effects.

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