TROGLITAZONE, METFORMIN, &SULFONYLUREA IN INSULIN STIMULATED GLUCOSE

$3,034M01FY2000RRNIH

University Of Pittsburgh At Pittsburgh, Pittsburgh PA

Investigators

Linked publications & trials

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Abstract

The objective of this study is to assess the potential mechanism by which Troglitazone improves skeletal muscle insulin sensitivity in patients with Non-Insulin Dependent Diabetes Mellitus (NIDDM) and compare these to the effects of Metformin and sulfonylurea treatments. The hypothesis to be tested is that troglitazone has a greater effect to improve skeletal muscle insulin sensitivity than does metformin or sulfonylurea therapy.

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